Train-the-trainer (TTT) programs are frequently used to facilitate knowledge dissemination. However, little is known about the effectiveness of these programs. Through a systematic review and meta-analysis, the authors assessed the impact of train-the-trainer programs on learning and behavior of trainers for educating health and social professionals (trainees). The results of this study including 16 unique studies out of 11,202 potentially eligible references, show that the targeted trainers were mostly nurses and physicians. The most frequent measured outcome was knowledge. TTT programs demonstrated significant effect on knowledge. No studies measured trainers’ ability to deliver the training program. The authors conclude that TTT programs may improve the knowledge of trainers. However, the heterogeneity and small number of studies hamper our ability to draw conclusions that are more robust. Click here to read more.