Authors aimed to identify factors associated with decision regret among informal caregivers engaging in housing decisions for cognitively impaired older adults. The study showed that the mean of decision regret of informal caregivers was 12.4 out of 100. Factors associated with more decision regret were being retired compared to being a homemaker, higher burden of care, and higher decisional conflict. These findings will allow risk-mitigation strategies for informal caregivers at risk of experiencing regret.